Table 4.

Total, direct and indirect effects of socio-economic position on health-related quality of life (EQ-5D-5L), social difficulties index (SDI) and for those working at diagnosis, not returning to work, with number of comorbidities the mediator (unstandardised coefficients (Coeff) or odds ratios (ORs) reported)^{^,#,$}

Effect	Variable	EQ-5D-5L index			SDI			Not in work force
		Coeff	95% CI		Coeff	95% CI		OR	95% CI
			Lower	Upper		Lower	Upper		Lower	Upper
Index of relative socio-economic disadvantage (IRSD) mediated through comorbidities
Total	IRSD-10	0.006	0.001	0.0100	− 0.210	− 0.336	− 0.085	0.89	0.800	0.996
Direct	IRSD-10	0.005	0.001	0.009	− 0.180	− 0.302	− 0.068	0.90	0.81	1.003
Indirect	Through comorbidities	0.001	0.00	0.002	− 0.030	− 0.065	− 0.002	1.00	0.98	1.015
If significant: % of association mediated		17%			14%			ns
Index of relative socio-economic disadvantage (IRSD) mediated through information needs
Total	IRSD-10	0.006	0.002	0.010	− 0.210	− 0.336	− 0.085	0.893	0.800	0.996
Direct	IRSD-10	0.005	0.001	0.009	− 0.190	− 0.309	− 0.071	0.882	0.791	0.984
Indirect	Through information needs	0.001	− 0.001	0.002	− 0.021	− 0.061	0.019	1.004	0.989	1.021
If significant: % of association mediated		ns			ns			ns

^{^}IRSD-10, index of relative socio-economic disadvantage (deciles)

^#Analyses adjusted for time since diagnosis, age, gender, cancer type, time since diagnosis, treatment response, country of birth and residential location

^$Estimates based on 5000 bootstrapped samples