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. 2022 Apr 27;8:234. doi: 10.1038/s41420-022-01011-7

Fig. 1. BMP4 is upregulated in human, mice with NAFLD and FFA-induced hepatocytes.

Fig. 1

a Serum BMP4 levels in patients with or without NAFLD, *P < 0.05. b Relative mRNA expression levels of BMP4 in mice with HFD, HFFD, or regular chow diet, *compared to control, p < 0.05, **compared to control, p < 0.001. c Western blot analysis of BMP levels in mice with HFD, HFFD, or regular chow diet. d Immunohistochemistry of BMP4 in mice with HFD, HFFD, or regular chow diet. e IF of BMP4 in FFA-induced HepG2 and LO2 cells. f Western blot analysis of BMP levels in FFA-induced HepG2 and LO2 cells. g Relative mRNA expression levels of BMP4 in FFA-induced HepG2 and LO2 cells, *compared to control, p < 0.05, **compared to control, p < 0.001.