Table 2.
Tumor Responses
| Variables | Pem-Based CTx | Lorlatinib | p Value |
|---|---|---|---|
| All patients, n | 22 | 16 | |
| Best overall response, n (%) | |||
| CR | 0 | 0 | |
| PR | 10 (45) | 7 (44) | |
| SD | 8 (36) | 3 (19) | |
| PD | 4 (18) | 4 (25) | |
| NE | 0 | 2 (13) | |
| Clinical benefit, % | |||
| ORR | 45 | 44 | 0.9169 |
| DCR | 82 | 63 | 0.1818 |
CR, complete response; CTx, chemotherapy; DCR, disease control rate; NE; not evaluable; ORR, objective response rate; PD, progression disease; Pem, pemetrexed; PR, partial response; SD, stable disease.