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. 2022 Apr 14;12:873020. doi: 10.3389/fonc.2022.873020

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Copyright © 2022 Tan, Xia, Zhang, Xu, Liu, Guo and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TRAM2 was identified as a potential target regulated by RBM15B. (A) KEGG analysis of the RIP-seq data. (B) A GEO dataset (GSE105130) was used for GSEA. (C) Identification of RBM15B-related genes through a joint analysis of multiple databases. (D) Detection of TRAM2 expression in Huh-7 cells with stable RBM15B knockdown. (E, F) Correlation between RBM15B and TRAM2 expression levels. (G) RIP-qPCR results showing the correlation between RBM15B and TRAM2 mRNA levels. (H) Schematic representation of TRAM2 mRNA depicting fragments used for biotin pull-down assays. *p < 0.05; **p < 0.01; ***p < 0.001. ns means no significant difference.