TABLE 2.
Methods and results of included studies.
| Author | Country | Economic evaluation methods | Discount (cost | effect) | Total cost | LYS | QALY | △Cost | △LYS | △QALY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | B | A | B | A | B | |||||||
| Savira et al., 2021 (Savira et al., 2021) | Australia | CEA,CUA | 5% | 5% | $28,445,855 | $24,753,415 | 4,047 | 3,631 | 2,789 | 2,502 | $3,692,440 | 416 | 287 |
| Parizo et al., 2021 (Parizo et al., 2021) | United States | CEA,CUA | 3% | 3% | $183 583 | $ 145,371 | 7.60 | 7.00 | 5.70 | 5.20 | $38,212 | 0.60 | 0.50 |
| Mendoza et al., 2021 (Mendoza et al., 2021) | The Philippines | CUA | 3% | 3% | - | - | - | - | - | - | - | - | - |
| Liao et al., 2021 (Liao et al., 2021) | Taiwan, China | CEA,CUA | 3% | 3% | $87,805 | $76,501 | 14.71 | 13.46 | 11.03 | 10.09 | $11,304 | 1.25 | 0.94 |
| Korea | CUA | 3% | 3% | $17,577 | $13,277 | - | - | 9.56 | 8.74 | $4,300 | - | 0.82 | |
| Australia | CUA | 3% | 3% | $59,126 | $50,745 | - | - | 9.85 | 9.01 | $8,381 | - | 0.84 | |
| Japan | CUA | 3% | 3% | $49,064 | $35,453 | - | - | 9.56 | 8.74 | $13,611 | - | 0.82 | |
| Singapore | CUA | 3% | 3% | $160,525 | $140,153 | - | - | 10.29 | 9.42 | $20,372 | - | 0.87 | |
| Rungroj et al., 2021 (Krittayaphong and Permsuwan, 2021) | Thailand | CUA | 3% | 3% | THB54,405 | THB17,442 | 10.23 | 9.35 | 6.92 | 6.33 | THB36,963 | 0.88 | 0.59 |
| Isaza et al., 2021 (Isaza et al., 2021) | United States | CEA,CUA | 3% | 3% | $193,400 | $150,600 | 6.60 | 5.91 | 5.36 | 4.73 | $42,800 | 0.69 | 0.63 |
| Yao et al., 2020 (Yao et al., 2020) | China | CEA,CUA | 4.2% | 4.2% | $5,829 | $4,377 | 7.11 | 6.60 | 4.82 | 4.44 | $1,452 | 0.51 | 0.38 |
| Phil et al., 2020 (McEwan et al., 2020) | Spain | CEA,CUA | 3% | 3% | €24,330 | €19,642 | 6.35 | 5.74 | 4.70 | 4.22 | €4,688 | 0.61 | 0.48 |
| Germany | CEA,CUA | 3% | 3% | €25,328 | €22,647 | 6.35 | 5.74 | 4.72 | 4.22 | €2,681 | 0.61 | 0.50 | |
| United Kingdom | CEA,CUA | 3% | 3% | £16,408 | £13,628 | 6.20 | 5.62 | 4.61 | 4.13 | £2,780 | 0.58 | 0.48 | |
| Author | Country | Discount year | ICER | Local currency in 2020 | ICER, USD (PPP 2021) | WTP | Funding source | |
|---|---|---|---|---|---|---|---|---|
| /LYS | /QALY | /QALY | /QALY | |||||
| Savira et al., 2021 (Savira et al., 2021) | Australia | 2020 | $8,875 | $12,842 | $12,842 | $12,842 | $50,000 | Monash International Postgraduate Research Scholarship; Monash Graduate Scholarship |
| Parizo et al., 2021 (Parizo et al., 2021) | United States | 2020 | $68,819 | $83,650 | $83,650 | $83,650 | $50,000∼$150,000 | National Heart, Lung, and Blood Institute of the National Institutes of Health |
| Mendoza et al., 2021 (Mendoza et al., 2021) | The Philippines | 2019 | - | PHP188,450 | PHP193,406 | $9,913 | PHP180,500 | AstraZeneca Pharmaceuticals (Phils) |
| Liao et al., 2021 (Liao et al., 2021) | Taiwan, China | 2020 | $9,080 | $12,305 | $12,305 | $12,305 | $25,000∼$75,000 | Ministry of Science and Technology in Taiwan |
| Korea | 2020 | - | $5,277 | $5,277 | $5,277 | $30,000 | ||
| Australia | 2020 | - | $9,980 | $9,980 | $9,980 | $52,000 | ||
| Japan | 2020 | - | $16,705 | $16,705 | $16,705 | $39,000 | ||
| Singapore | 2020 | - | $23,227 | $23,227 | $23,227 | $58,000 | ||
| Rungroj et al., 2021 (Krittayaphong and Permsuwan, 2021) | Thailand | 2019 | THB42,173 | THB62,090 | THB61,565 | $4,990 | THB160,000 | - |
| Isaza et al., 2021 (Isaza et al., 2021) | United States | 2020 | $61,800 | $68,300 | $68,300 | $68,300 | $50,000∼$150,000 | Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology |
| Yao et al., 2020 (Yao et al., 2020) | China | 2017 | $2,809 | $3,827 | $4,041 | $4,041 | $8,773 | Key Projects in the National Science and Technology Pillar Program of the 13th Five‐Year Plan Period |
| Phil et al., 2020 (McEwan et al., 2020) | Spain | 2019 | - | € 9,406 | € 9,375 | $15,172 | €20,000 | AstraZeneca Pharmaceuticals (Phils) |
| Germany | 2019 | - | € 5,379 | € 5,406 | $7,252 | €20,000 | ||
| United Kingdom | 2019 | - | £5,822 | £5,879 | $8,399 | £20,000 | ||
CEA, cost-effectiveness analysis; CUA, cost-utility analysis; LYS, life year saved; QALY, quality-adjusted life year; △Cost, increment cost; △LYS, increment life year saved; △QALY, increment quality-adjusted life year; A, intervention; B, comparator, ICER, increment cost-effectiveness ration; PPP, purchasing power parity; WTP, willingness to pay.