Table 2.

Haplotype frequencies of the D614G group mutations in early samples from Europe.

Haplotype	Jan-01 2020 (0)	Jan-11 2020 (0)	Jan-21 2020 (1)	Jan-31 2020 (31)	Feb-10 2020 (32)	Feb-20 2020 (37)	Mar-01 2020 (592)	Mar-11 2020 (4049)	Mar-21 2020 (8323)	Mar-31 2020 (13 677)
CCCA (0000)	0	0	0	23	19	18	234	1236	2432	3259
TTTG (1111)	0	0	1	1	7 (9)	18	344	2723	5741	10 184
vs. CCCA					0.21	1.00	1.47	2.20	2.36	3.12
Dw					0.54	0.28	0.25	0.17	0.28	AVG ∼ +0.30
TTCG (1101)	0	0	0	7	6	1	5 (6)	7	4	7 (11)
vs. CCCA				0.30	0.32		0.024	0.0057		0.0019
Dw				−0.84	−1.03		−0.85	−0.55		AVG ∼ −0.82
TCTG (1011)	0	0	0	0	0	0	2	4 (6)	9	11
vs. CCCA								0.0041	0.0037	0.0034
Dw								−0.094	−0.085	AVG ∼ −0.090
CTTG (0111)	0	0	0	0	0	0	0	5	11	8
vs. CCCA								0.0040	0.0045	0.0025
Dw								−0.24	−0.59	AVG ∼ −0.42

Table 2 is the counterpart of Table 1 in Europe with the additional information on the relative fitness of different haplotypes. D_w is the fitness advantage of the focus haplotype over DG0000 with the fitness defined by R in . D_w = R_X − R_Y where X is for any haplotype X and R_Y is for DG0000. AVG is D_w averaged across time periods.