. 2022 Mar 12;4(5):100447. doi: 10.1016/j.xkme.2022.100447

Table 1.

Characteristics of Included Studies

Author	Year of Publication	Total Patient Number	No. of CKM Patients	No. of Dialysis Patients	Country	Age Inclusion (y)	Median Age CKM (y)	Median Age Dialysis (y)	Study Design	Comorbidity Scale	Measure of Overall Comorbidity	SDM	KSC Input
Joly²⁰	2003	144	37	107	France	≥80	84.1^a	83^a	Retrospective	Own	32.4% ≥3 comorbidities	Yes	Unclear
Smith³⁰	2003	321	34	196	England	All	71	59	Retrospective	Own	Mean comorbidity score^b 4.7 (SD 3)	Yes	Yes
Murtagh²¹	2007	129	77	52	England	≥75	83		Retrospective	Davies	18.2% Davies grade 2 score	Yes	Unclear
Carson²⁹	2009	202	29	173	England	≥70	83	82	Prospective	CCI	Mean CCI 13.7	Yes	Unclear
Ellam⁴⁸	2009	69	69	0	England		80	N/A	Retrospective	SCG	Stoke's comorbidity score 2 = 24%-28%	Yes	Unclear
Wong²³	2007	73	73	0	England	All	79		Prospective	SCG	Stoke's comorbidity grade=1	Yes	Yes
Chandna²⁴	2011	844	106	689	England	All	81		Retrospective	Own	Comorbidity score^b > 4 in 50.9%	Yes	Yes
Da Silva-Gane¹¹	2012	170	30	124	England	All	77.5^a	83 (HD), 78 (PD)	Prospective	Own	Comorbidity score >3 in 74%	Yes	Yes
Hussain³³	2013	441	172	269	England		NR, enrolled >70 years	NR	Prospective	NR	NR	Yes	Yes
Seow²⁶	2013	101	63	38	Singapore	≥75	78	60	Prospective	CCI	Mean CCI 5	Unclear	Unclear
Shum²⁵	2013	199	42	157	Hong Kong	≥65	75.3^a	73^a	Retrospective	CCI	Mean CCI 4.6	Yes	Yes
Brown³⁵	2015	467	122	345	Australia	All	82	67	Prospective	CCI	57% had ≥2 comorbidities	Yes	Yes
Kwok²⁷	2016	558	432	126	Hong Kong	≥65	80^a	78^a	Retrospective	CCI	CCI 9	Unclear	Unclear
Echevers²²	2016	314	93	69	Spain	≥70	78	76	Retrospective	CCI	CCI 8	Unclear	Unclear
Verberne³¹	2016	311	107	204	Netherlands	>70	83^a	76^a	Retrospective	Davies	Davies grade ≥3	Yes	Yes
Reindl-Schwaighofer⁴²	2017	1018	174	844	Austria	≥65	81	74	Retrospective		NR
Raman³²	2018	204	81	123	United Kingdom	≥75	84	79	Prospective	NR	N/A		Unclear
Tam-Tham³⁴	2018	838	338	500	Canada	≥65	83^a	76^a	Retrospective	NR	NR	Unclear	Unclear

Note: Measures of overall comorbidity –CCI, Charlson Comorbidity Index; Davies, Davies Score; None, comorbidities not reported; Own: Author utilized own nonvalidated method of reporting; SCG, Stoke's Comorbidity Grade.

Abbreviations: CKM, Conservative kidney management; HD, haemodialysis; KSC, kidney supportive care; N/A, not applicable; NR, not reported; PD, peritoneal dialysis; SDM, shared decision making.

Mean age

Comorbidity score: cardiovascular disease, peripheral vascular disease, respiratory disease.