Subject	Cancer Research and Cell Biology
Specific subject area	Electrophysiology of store operated calcium in androgen resistant prostate cancer and its associated impact on disease cell biology.
Type of data	Graph Figure
How the data were acquired	Cell culture Protein fractionation qPCR – Roche Nano Lightcycler Western blot – Image measurement ImageJ Fura-2am fluorescent Calcium measurement using a Wallac 1420 Victor2 Microplate Reader Colony formation assay Statistical Analysis: GraphPad Prism Data Collection – qPCR and Calcium measurement data was collected from computer. Western blot images were scanned and analysed with ImageJ. All other data was recorded manually on an excel file and processed accordingly.
Data format	Raw Analyzed
Description of data collection	Androgen sensitive prostate cancer cell line, LNCaP, was subject to (1) DMSO vehicle or ADT Bicalutamide (2) 10 days (LNCaP-ADT) or (3) 2 years (LNCaP-ABL). In addition to androgen insensitive, PC3. All with or without treatment of calcium channel blocker, nifedipine. Extracted RNA and protein
	was used to measure expression via qPCR and Western blot respectively. Store operated calcium was measured via FURA-2am. Cell proliferation was assessed with WST-1 assay.
Data source location	Dublin City University, National Institute of Cellular Biotechnology and the School of Nursing and Human Science, Dublin, Ireland.
Data accessibility	Repository name: Mendeley Data Data identification number: 10.17632/d9vn7ygf3z.4 Direct URL to data: https://data.mendeley.com/datasets/d9vn7ygf3z/5
Related research article	For an article published in Cell Calcium. D. O'Reilly, T. Downing, S. Kouba, M. Potier-Cartereau, D.J. McKenna, C. Vandier, P. Buchanan. CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer. Cell Calcium. Volume 103, May 2022, 102554. https://doi.org/10.1016/j.ceca.2022.102554