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Our framework DPMIL for molecular subtype prediction. The pipeline of out framework contains 5 stages. (1) WSIs are divided into patches. (2) ResNet trained with Co-teaching generate feature for each patch. (3) LOF is adopted to select discriminative patches based on features. (4) Discriminative patches are used to finetune ResNet with WSI and patch loss. (5) Finetuned model predict final molecular subtypes for patches and WSIs.
