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. 2022 Apr 14;12:864933. doi: 10.3389/fcimb.2022.864933

Table 3.

Comparison of Demographics, Comorbidities, Outcomes, Baseline Liver Biochemistry, and Ultrasound Results between Subgroups Stratified by the Number of Liver Function Tests Abnormalities at 4 Follow-up Time Points.

Variable 0 times 1-2 times 3-4 times P value
n 107 44 16
Age, median (IQR), y 45 (35, 57) 44 (35, 51) 42 (36, 55) 0.900
Sex, male, n (%) 41 (38.3%) 26 (59.1%) 14 (87.5%) <0.001
Body mass index, median (IQR), kg/m² 22.9 (21.0, 25.1) 23.9 (21.5, 26.0) 25.8 (23.5, 27.1) 0.003
Any kind of comorbidities, n (%) 24 (22.4%) 15 (34.1%) 1 (6.2%) 0.072
Hepatitis B infection 8 (7.5%) 7 (15.9%) 0 (0.0%) 0.120
Disease severity, severe/critical, n (%) 18 (16.8%) 5 (11.4%) 7 (43.8%) 0.021
LFT abnormality at admission, n (%) 20 (18.7%) 18 (40.9%) 15 (93.8%) <0.001
LFT abnormality at discharge, n (%) 21 (19.6%) 24 (54.5%) 14 (87.5%) <0.001
Ultrasound findings of liver at 12 months
Parenchymal echo <0.001
Normal 74 (80.4%) 32 (74.4%) 4 (28.6%)
Fatty liver 17 (18.5%) 9 (20.9%) 10 (71.4%)
Coarsened echo 1 (1.1%) 2 (4.7%) 0 (0.0%)
Oblique diameter of right lobe 129 (116, 137) 135 (128, 141) 142 (130, 152) 0.003

7 missing, 18 missing.

IQR, interquartile range; ICU, intensive care unit; LFT, liver function tests.