Table 3.
Comparison of Demographics, Comorbidities, Outcomes, Baseline Liver Biochemistry, and Ultrasound Results between Subgroups Stratified by the Number of Liver Function Tests Abnormalities at 4 Follow-up Time Points.
Variable | 0 times | 1-2 times | 3-4 times | P value |
---|---|---|---|---|
n | 107 | 44 | 16 | |
Age, median (IQR), y | 45 (35, 57) | 44 (35, 51) | 42 (36, 55) | 0.900 |
Sex, male, n (%) | 41 (38.3%) | 26 (59.1%) | 14 (87.5%) | <0.001 |
Body mass index, median (IQR), kg/m² † | 22.9 (21.0, 25.1) | 23.9 (21.5, 26.0) | 25.8 (23.5, 27.1) | 0.003 |
Any kind of comorbidities, n (%) | 24 (22.4%) | 15 (34.1%) | 1 (6.2%) | 0.072 |
Hepatitis B infection | 8 (7.5%) | 7 (15.9%) | 0 (0.0%) | 0.120 |
Disease severity, severe/critical, n (%) | 18 (16.8%) | 5 (11.4%) | 7 (43.8%) | 0.021 |
LFT abnormality at admission, n (%) | 20 (18.7%) | 18 (40.9%) | 15 (93.8%) | <0.001 |
LFT abnormality at discharge, n (%) | 21 (19.6%) | 24 (54.5%) | 14 (87.5%) | <0.001 |
Ultrasound findings of liver at 12 months ‡ | ||||
Parenchymal echo | <0.001 | |||
Normal | 74 (80.4%) | 32 (74.4%) | 4 (28.6%) | |
Fatty liver | 17 (18.5%) | 9 (20.9%) | 10 (71.4%) | |
Coarsened echo | 1 (1.1%) | 2 (4.7%) | 0 (0.0%) | |
Oblique diameter of right lobe | 129 (116, 137) | 135 (128, 141) | 142 (130, 152) | 0.003 |
† 7 missing, ‡ 18 missing.
IQR, interquartile range; ICU, intensive care unit; LFT, liver function tests.