Table 4.
Linear regression models of Shannon Diversity Index in OcMMP vs. healthy controls.
| Variables | Univariable models | Multivariable models | ||
|---|---|---|---|---|
| Coefficient (95% CI) | p-Value | Coefficient (95% CI) | p-Value | |
| Cohort (OcMMP) | -0.57 (-0.86, -0.27) | <0.001 | -0.68 (-1.03, -0.33) | <0.001 |
| Age (per decade) | 0.11 (-0.05, 0.26) | 0.182 | 0.11 (-0.06, 0.27) | 0.198 |
| Gender (Female) | 0.02 (-0.31, 0.34) | 0.921 | 0.19 (-0.15, 0.54) | 0.266 |
| BMI (per 5kg/m2) | -0.05 (-0.18, 0.10) | 0.537 | 0.01 (-0.14, 0.16) | 0.919 |
| Diet (Standard diet) | 0.02 (-0.49, 0.52) | 0.945 | 0.42 (-0.11, 0.96) | 0.120 |
| PPI use (Yes) | 0.16 (-0.39, 0.70) | 0.564 | 0.31 (-0.23, 0.85) | 0.255 |
Results are from linear regression models. The coefficient represents the increase in the number of OTUs per the stated number of units increase for continuous variables, or for the stated category relative to the reference category for nominal variables. Bold p-values are significant at p<0.05. The number of participants in each group of the categorical variables are as per Table 1 .