Table 2.
Meta-Regression–derived Age-related Relative Change in Odds Ratio Associated With N501Y-Positive and Probable Delta Variants of Concern
| Variant | Outcome | Relative Odds Ratio | 95% Confidence Interval | τ2a | R2b(%) |
|---|---|---|---|---|---|
| Probable Delta | |||||
| Hospitalization | 0.99 | .89–1.09 | 0.102 | 2.94 | |
| ICU admission | 0.90 | .76–1.07 | 0.0966 | 25.67 | |
| Death | 0.85 | .64–1.13 | 0.2064 | 26.98 | |
| N501Y-positive | |||||
| Hospitalization | 1.00 | .95–1.05 | 0.0154 | 0 | |
| ICU admission | 0.95 | .86–1.06 | 0.0147 | 2.12 | |
| Death | 0.98 | .84–1.14 | 0.0414 | 0 | |
Age category treated as a 9-level ordinal variable for the purpose of estimating linear trends. Coefficients can be interpreted as change in risk per 10-year change in age category.
Abbreviation: ICU, intensive care unit.
Estimated amount of residual heterogeneity due to between-age group variation.
Fraction of heterogeneity accounted for by including age in meta-regression models.