Table I.
Baseline characteristics and first trimester pregnancy outcomes in the UK in 2020 by SARS-CoV-2 infection status.
| Outcomes | Presumed infected (n=77) | Uncertain (n=295) | Presumed uninfected (n=2669) | P value |
|---|---|---|---|---|
| Median age [IQR] | 31 [27-39] | 32 [29-35] | 34 [30-36] | 0.13 |
| Median GA at recruitment | 8 [6-9] | 7 [5-10] | 7 [5-9] | 0.07 |
| Median BMI (kg/m2) [IQR] | 24 [23-31] | 25 [20-32] | 24 [22-29] | 0.06 |
| Ethnicity | 0.94 | |||
| White - n (%) | 69 (90) | 270 (92) | 2425 (91) | |
| BAME - n (%) | 5 (6) | 14 (5) | 154 (6) | |
| Did not disclose - n (%) | 3 (4) | 11 (4) | 90 (3) | |
| Smokers - n (%) | 1 (1) | 11 (4) | 94 (4) | 0.56 |
| Type of conception | 0.48 | |||
| Natural - n (%) | 71 (92) | 281 (95) | 2501 (94) | |
| Fertility treatment - n (%) | 6 (8) | 14 (5) | 168 (6) | |
| Previous early miscarriages < 13 wk – n (%) | 0.06 | |||
| 0 | 57 (74) | 215 (73) | 2126 (80) | |
| 1 or 2 | 18 (23) | 71 (24) | 467 (17) | |
| ≥ 3 | 2 (3) | 9 (3) | 76 (3) | |
| Ongoing pregnancy at 13 wk - n (%) | 66 (86) | 279 (95) | 2436 (91) | 0.03 |
| Miscarriage < 13 wk - n (%) | 11 (14) | 15 (5) | 212 (8) | 0.02 |
| Median GA at miscarriage diagnosis | 9 [8-11] | 9 [8-12] | 9 [8-11] | 0.95 |
| Termination of pregnancy - n (%) | 0 (0) | 1 (0) | 9 (0) | 0.71 |
| Other (molar/ectopic/PUL) - n (%) | 0 (0) | 0 (0) | 12 (0) | 0.48 |
SARS-CoV-2: severe acute respiratory syndrome coronavirus, IQR: interquartile range, GA: gestational age, BAME: Black, Asian and minority ethnic PUL: pregnancy of unknown location, wk: weeks. We used non-parametric tests to compare medians and chi square test to compare proportions. Bold indicates statistical significance.