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. 2022 Apr 6:jiac118. doi: 10.1093/infdis/jiac118

Figure 2.

Figure 2.

Vaccine effectiveness of mRNA vaccination against coronavirus disease 2019 (COVID-19) hospitalization by immune status group. Separate estimates were calculated for 2 doses of an mRNA vaccine and 3 doses of an mRNA vaccine. *Models were adjusted for calendar time of admission (in biweekly intervals), US Health and Human Services region, age group (18–49, 50–64, or ≥65 years), sex, and race and Hispanic ethnicity. Post hoc P value comparisons of vaccine effectiveness for 2 doses vs 3 doses of an mRNA vaccine were obtained using the pwcompare function in Stata §Defined as receiving supplemental oxygen support or having a documented oxygen saturation <92% within 24 hours of admission. This analysis was restricted to cases who met criteria for hypoxemia within 24 hours of admission and all control patients (ie, including those with or without hypoxemia).