Table 3.
In-Hospital Clinical Outcomes Among COVID-19 Cases by Vaccination Status Within Each of the 3 Immune Status Groups (See Separate Upload per Format per Guidelines)
| Outcome, No./ Total No. (%)a | Group 1: Solid Organ Transplant Recipients | Group 2: Other Immunocompromising Condition | Group 3: Immunocompetent | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Vaccinated With 2 or 3 Doses (n = 163) | Unvaccinated (n = 64) | P Valueb | Vaccinated With 2 or 3 Doses (n = 253) | Unvaccinated (n = 333) | P Value | Vaccinated With 2 or 3 doses (n = 757) | Unvaccinated (n = 3362) | P Value | |
| In-hospital death (within 28 days) | 30 (18) | 8 (13) | .28 | 37 (15) | 44 (13) | .62 | 79 (10) | 349 (10) | .96 |
| Invasive mechanical ventilation | 35 (21) | 11 (17) | .47 | 38 (15) | 58 (17) | .44 | 98 (13) | 847 (25) | <.001 |
| Noninvasive ventilation | 30 (18) | 8 (13) | .28 | 47 (19) | 58 (17) | .72 | 101 (13) | 583 (17) | .008 |
| Vasopressor use | 36 (22) | 12 (19) | .58 | 41 (16) | 63 (19) | .39 | 93 (12) | 790 (23) | <.001 |
| New renal replacement therapy | 14 (9) | 6 (9) | .85 | 9 (4) | 17 (5) | .37 | 39 (5) | 194 (6) | .51 |
| ICU admission | 74 (45) | 19 (30) | .03 | 81 (32) | 119 (36) | .35 | 203 (27) | 1441 (43) | <.001 |
| Hospital length of stay, median (IQR) | 6 (4–11) | 6 (4–8) | .60 | 5.5 (3–10) | 6 (3–11) | .29 | 5 (3–9) | 6 (3–10) | <.001 |
Abbreviations: ICU, intensive care unit; IQR, interquartile range.
Results provided for COVID-19 case patients who had information available on clinical outcomes (outcomes were not available for 38 of 4970 [0.8%] COVID-19 case patients); outcomes were censored at 28 days from the date of hospital admission.
P value comparisons between vaccinated and unvaccinated cases were calculated using the Pearson’s χ2 test for categorical variables and Wilcoxon rank-sum test for continuous variables.