Table 2.
Top hits of meta-analysis of wLE in PD discovery (PDI) and replication sample (PDII)
| CpG | beta_meta | p_meta | p_meta_corrected | beta_PDI | p_PDI | beta_PDII | p_PDII |
|---|---|---|---|---|---|---|---|
| cg09738429 | − 0.2656 | 6.40 × 10−06 | 1.00 | − 0.2798 | 2.36 × 10−04 | − 0.2382 | 2.05 × 10−02 |
| cg03341655 | − 0.1077 | 8.14 × 10−06 | 1.00 | − 0.0686 | 1.67 × 10−01 | − 0.1201 | 3.98 × 10−05 |
beta_meta: effect-size estimate in meta-analysis
p_meta: nominal p-value from meta-analysis
p_meta_corrected: Benjamini–Hochberg FDR-corrected p-value from meta-analysis
beta_PDI: effect-size estimate in PDI
p_PDI: nominal p-value in PDI
beta_PDII: effect-size estimate in PDII
p_PDII: nominal p-value in PDII