EC50 values of 1,4-benzoxazin-3-ones against Psa, Xac and Xooa.
| Compd | Xoo | Xac | Psa | |||
|---|---|---|---|---|---|---|
| Regression equation | EC50 (μg mL−1) | Regression equation | EC50 (μg mL−1) | Regression equation | EC50 (μg mL−1) | |
| 4b | y = 0.5434x + 4.1434 | 37.70 ± 1.63 | y = 1.0179x + 3.3998 | 37.33 ± 1.46 | — | — |
| 4d | y = 0.7887x + 3.8552 | 28.28 ± 2.42 | y = 1.2451x + 3.682 | 11.44 ± 1.73 | y = 0.5991x + 3.8205 | 93.07 ± 1.54 |
| 4e | y = 1.2439x + 3.6936 | 11.23 ± 1.16 | y = 1.7851x + 3.0969 | 11.64 ± 1.27 | y = 0.8778x + 3.7733 | 24.97 ± 2.33 |
| 4m | y = 1.1474x + 3.3538 | 27.21 ± 1.61 | y = 2.1693x + 2.57 | 13.19 ± 1.28 | y = 1.0277x + 3.5593 | 25.23 ± 1.32 |
| 4n | y = 1.9139x + 3.6705 | 4.95 ± 0.73 | y = 1.7394x + 3.8296 | 4.71 ± 0.52 | y = 1.1107x + 3.9675 | 8.50 ± 0.83 |
| BTb | y = 1.2472x + 2.5681 | 89.10 ± 1.96 | — | — | y = 1.7949x + 1.2883 | 116.9 ± 1.71 |
| TCb | y = 1.1471x + 2.5854 | 127.3 ± 1.50 | y = 1.6235x + 1.8867 | 82.73 ± 1.45 | y = 1.9802x + 1.1106 | 87.50 ± 1.42 |
a
Average of three replicates; BT: bismerthiazol; TC: thiadiazole copper.
b
The antibacterial agents applied to compare antibacterial activities.