Table 1:
Characteristics of the pathological cohort
| Case No. | Path diagnosis | Age at death (years) | Sex | In vivo MRI-death interval (months) | Post-mortem interval (h) | MRI-visible PVS score (CSO) on in vivo MRI | MRI-visible PVS score (CSO) on ex vivo MRI | MRI-visible PVS score (BG) on in vivo MRI | MRI-visible PVS score (BG) on ex vivo MRI | Hypertension | Clinical presentation |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CAA | 80 | M | 16 | N/A | 3 | 4 | 0 | 1 | Yes | Transient focal neurological episodes |
| 2 | CAA | 70 | M | N/A | 16 | N/A | 4 | N/A | 0 | Yes | ICH |
| 3 | CAA | 76 | M | 17 | 27 | 4 | 4 | 1 | 1 | No | ICH Cognitive Impairment |
| 4 | CAA | 65 | M | 8 | 14 | 4 | 4 | 0 | 1 | No | ICH |
| 5 | CAA | 81 | M | 5 | N/A | 2 | 2 | 1 | 1 | Yes | Transient focal neurological episodes |
| 6 | CAA | 70 | F | 14 | N/A | 4 | 4 | 2 | 2 | Yes | ICH |
| 7 | CAA | 67 | M | 14 | N/A | 3 | 3 | 2 | 2 | No | ICH |
| 8 | CAA | 69 | M | 6 | 36 | 4 | 4 | 1 | 1 | No | ICH |
| 9 | CAA | 64 | F | 60 | 30 | 3 | 3 | 1 | 1 | No | ICH Cognitive Impairment |
| 10 | CAA | 79 | F | 55 | 37 | 3 | 4 | 3 | 2 | Yes | ICH |
| 11 | CAA | 67 | M | 18 | 24 | 3 | 4 | 1 | 1 | Yes | ICH Transient focal neurological episodes |
| 12 | CAA | 88 | F | N/A | 11 | N/A | 3 | N/A | 1 | Yes | ICH |
| 13 | CAA | 67 | F | 5 | 16 | 4 | 4 | 1 | 1 | No | Transient focal neurological episodes Cognitive Impairment |
| 14 | CAA | 84 | F | 53 | 32 | 2 | 4 | 1 | 2 | Yes | N/A |
| 15 | CAA | 67 | M | 78 | N/A | 2 | 2 | 1 | 1 | Yes | ICH |
| 16 | CAA | 76 | M | 157 | 20 | 3 | 4 | 0 | 1 | No | ICH |
| 17 | CAA | 78 | F | 47 | 24 | N/A | 2 | N/A | 1 | N/A | ICH |
| 18 | CAA | 86 | M | 53 | 20 | 3 | 4 | 2 | 3 | Yes | Cognitive Impairment |
| 19 | CAA | 85 | M | 66 | N/A | 0 | 2 | 0 | 3 | Yes | ICH |
| 1 | No-CAA | 90 | M | 47 | N/A | N/A | 2 | N/A | 2 | No | No neurological diagnoses |
| 2 | No-CAA | 95 | F | 70 | 4 | 1 | 2 | 0 | 2 | Yes | TIA |
| 3 | No-CAA | 88 | F | 17 | 9 | 3 | 4 | 1 | 4 | Yes | Cognitive Impairment |
| 4 | No-CAA | 85 | M | 7 | 38 | 1 | 3 | 2 | 1 | Yes | Cognitive Impairment |
| 5 | No-CAA | 82 | F | 25 | N/A | 3 | 3 | 2 | 2 | Yes | Cognitive Impairment |
Table 1 Characteristics of the pathological cohort. Key: M, male; F, female; CAA, cerebral amyloid angiopathy; CSO, centrum semiovale; BG, basal ganglia; N/A, not available; ICH, intracerebral hemorrhage; TIA, transient ischemic attack. Diagnoses of arterial hypertension during life and clinical phenotype were extracted from available medical records.