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. 2022 Apr 14;10:832363. doi: 10.3389/fped.2022.832363

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Copyright © 2022 Zhang, Amat, Tang, Chen, Tian, Hu, Chen, Shen and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nudix hydrolase 15 (NUDT15) gene variants identified by Sanger sequencing. (A) c.55_56insGAGTCG and c.52G>A heterozygous variant in exon 1. (B) Rare heterozygous variants c.137C>G and c.138T > G in exon 1 were confirmed. (C) c. 415C > T heterozygous and homozygous variant in exon 3.