TABLE 5.

Rare NUDT15 variants among Han and ethnic minority populations.

Genetic variant	Protein alteration	Exon	Ethnicity	Protein abundance score (26)	Drug sensitivity score (26)	Final classification (26)
c.37G > A	G13R	exon1	Han	0.78	1.27	wt-like
c.137C > G and c.138T > G	P46R	exon1	Uighur	0.14	0.04	damaging
c.154T > C	F52L	exon1	Han	/	1.07	/
c.202G > A	A68T	exon2	Han	1.06	1.00	wt-like
c.254T > C	I85T	exon2	Han	1.09	1.23	wt-like
c.272A > C	H91P	exon2	Han	0.49	0.62	wt-like
c.422T > G	L141*	exon3	Han	/	/	/