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. 2022 Apr 14;13:816689. doi: 10.3389/fimmu.2022.816689

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Copyright © 2022 Thiam, Wang, Barreto Sánchez, Zhang, Ding, Wang, Zhang, Zhang, Wang, Li, Wen and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of cecal microbiota genus with body weight post-infection, H/L ratio and SCFAs concentration in the caecum of SE-infected chickens at 7 and 21 dpi. Turquoise positive correlation; Salmon, negative correlation; *strong correlation (|R| > 0.55, p < 0.05). BW: body weight post-infection; H_L: heterophil/lymphocyte ratio; AC: acetate; PA: propionate; BA: butyrate; VA: valerate. In total 28 biological replicates were used to perform this analysis, including H7_SE: High H/L SE-infected 7 dpi (n = 8), L7_SE: Low H/L SE-infected 7 dpi (n = 7), H21_SE: high H/L SE-infected 21 dpi (n = 6) and L21_SE: Low H/L SE-infected 21 dpi (n = 7). *0.01 < P ≤ 0.05, **0.001 < P ≤ 0.01, ***P ≤ 0.001.