Table 4.
Top differentially abundant virulence factors between high and low H/L ratio SE-infected chickens based on VFDB database annotation.
| Dpi | Level 1 | Level 2 | VFs | Function | Species |
|---|---|---|---|---|---|
| 7 | Defensive virulence factors | Antiphagocytosis | Capsule | glycosyl transferase, group 2 family protein | E. Faecalis |
| Regulation of virulence-associated genes | Regulation | PhoP | Possible two component system response transcriptional positive regulator PhoP | M. Tuberculosis | |
| Nonspecific virulence factor | Iron uptake system | FbpABC | Iron (III) ABC transporter, ATP-binding protein | N. meningitidis | |
| Offensive virulence factors | Secretion system | HSI-I | serine/threonine protein kinase PpkA | P. aeruginosa | |
| 21 | Defensive virulence factors | Antiphagocytosis | Alignate | alginate biosynthesis regulatory protein AlgR | P. aeruginosa |
| Nonspecific virulence factor | Iron uptake system | FbpABC | Iron (III) ABC transporter, ATP-binding protein | N. meningitidis | |
| Regulation of virulence-associated genes | Regulation | PhoP/R | Possible two component system response transcriptional positive regulator PhoP | M. tuberculosis | |
| Offensive virulence factors | Adherence | Type IV pili | two-component response regulator PilR | P. aeruginosa | |
| ND | ND | Cytolysin | ND | ND |
Twenty-six birds were used, including H7: High H/L SE-infected 7 dpi (n = 7), L7: Low H/L SE-infected 7 dpi (n = 6), H21: high H/L SE-infected 21 dpi (n = 6) and L21: Low H/L SE-infected 21 dpi (n = 7). ND, Not determined.