TABLE 5.
The inheritance model analysis of these SNPs between CIN and control groups.
| SNPs | Model | Genotypes | Control (n%) | CIN (n%) | OR (95%CI) | p value | AIC | BIC |
|---|---|---|---|---|---|---|---|---|
| rs107822 | Codominant | T/T | 275 (39.4) | 101 (37.0) | 1.00 | 0.680 | 1,157.1 | 1,176.6 |
| C/T | 314 (45.0) | 124 (45.4) | 1.07 (0.79–1.46) | |||||
| C/C | 109 (15.6) | 48 (17.6) | 1.20 (0.80–1.81) | |||||
| Dominant | T/T | 275 (39.4) | 101 (37.0) | 1.00 | 0.500 | 1,155.4 | 1,170.1 | |
| C/T-C/C | 423 (60.6) | 172 (63.0) | 1.10 (0.83–1.48) | |||||
| Recessive | T/T-C/T | 589 (84.4) | 225 (82.4) | 1.00 | 0.440 | 1,155.3 | 1,169.9 | |
| C/C | 109 (15.6) | 48 (17.6) | 1.16 (0.80–1.68) | |||||
| Overdominant | T/T-C/C | 384 (55.0) | 149 (54.6) | 1.00 | 0.930 | 1,155.9 | 1,170.5 | |
| C/T | 314 (45.0) | 124 (45.4) | 1.01 (0.76–1.34) | |||||
| Log-additive | --- | --- | --- | 1.09 (0.90–1.33) | 0.380 | 1,155.1 | 1,169.8 | |
| rs10877887 | Codominant | T/T | 286 (41.0) | 126 (46.2) | 1.00 | 0.320 | 1,155.6 | 1,175.1 |
| C/T | 335 (48.0) | 123 (45.0) | 0.84 (0.62–1.12) | |||||
| C/C | 77 (11.0) | 24 (8.8) | 0.73 (0.44–1.21) | |||||
| Dominant | T/T | 286 (41.0) | 126 (46.2) | 1.00 | 0.160 | 1,153.9 | 1,168.5 | |
| C/T-C/C | 412 (59.0) | 147 (53.9) | 0.82 (0.62–1.08) | |||||
| Recessive | T/T-C/T | 621 (89.0) | 249 (91.2) | 1.00 | 0.360 | 1,155.1 | 1,169.7 | |
| C/C | 77 (11.0) | 24 (8.8) | 0.80 (0.49–1.30) | |||||
| Overdominant | T/T-C/C | 363 (52.0) | 150 (55.0) | 1.00 | 0.400 | 1,155.2 | 1,169.8 | |
| C/T | 335 (48.0) | 123 (45.0) | 0.89 (0.67–1.17) | |||||
| Log-additive | --- | --- | --- | 0.85 (0.68–1.05) | 0.130 | 1,153.6 | 1,168.3 | |
| rs2292832 | Codominant | T/T | 293 (42.0) | 114 (41.8) | 1.00 | 0.390 | 1,156.0 | 1,175.5 |
| T/C | 316 (45.3) | 132 (48.4) | 1.07 (0.80–1.45) | |||||
| C/C | 89 (12.8) | 27 (9.9) | 0.78 (0.48–1.26) | |||||
| Dominant | T/T | 293 (42.0) | 114 (41.8) | 1.00 | 0.960 | 1,155.9 | 1,170.5 | |
| T/C-C/C | 405 (58.0) | 159 (58.2) | 1.01 (0.76–1.34) | |||||
| Recessive | T/T-T/C | 609 (87.2) | 246 (90.1) | 1.00 | 0.200 | 1,154.2 | 1,168.9 | |
| C/C | 89 (12.8) | 27 (9.9) | 0.75 (0.47–1.18) | |||||
| Overdominant | T/T-C/C | 382 (54.7) | 141 (51.6) | 1.00 | 0.380 | 1,155.1 | 1,169.8 | |
| T/C | 316 (45.3) | 132 (48.4) | 1.13 (0.86–1.50) | |||||
| Log-additive | --- | --- | --- | 0.94 (0.76–1.16) | 0.570 | 1,155.6 | 1,170.2 | |
| rs353293 | Codominant | C/C | 499 (71.5) | 181 (66.3) | 1.00 | 0.280 | 1,155.3 | 1,174.9 |
| C/T | 180 (25.8) | 84 (30.8) | 1.29 (0.94–1.76) | |||||
| T/T | 19 (2.7) | 8 (2.9) | 1.18 (0.51–2.75) | |||||
| Dominant | C/C | 499 (71.5) | 181 (66.3) | 1.00 | 0.110 | 1,153.4 | 1,168.0 | |
| C/T-T/T | 199 (28.5) | 92 (33.7) | 1.28 (0.95–1.72) | |||||
| Recessive | C/C-C/T | 679 (97.3) | 265 (97.1) | 1.00 | 0.830 | 1,155.8 | 1,170.5 | |
| T/T | 19 (2.7) | 8 (2.9) | 1.10 (0.47–2.54) | |||||
| Overdominant | C/C-T/T | 518 (74.2) | 189 (69.2) | 1.00 | 0.120 | 1,153.5 | 1,168.1 | |
| C/T | 180 (25.8) | 84 (30.8) | 1.28 (0.94–1.74) | |||||
| Log-additive | --- | --- | --- | 1.21 (0.94–1.58) | 0.150 | 1,153.8 | 1,168.4 | |
| rs3746444 | Codominant | A/A | 490 (70.2) | 184 (67.4) | 1.00 | 0.460 | 1,156.4 | 1,175.9 |
| A/G | 183 (26.2) | 75 (27.5) | 1.09 (0.79–1.50) | |||||
| G/G | 25 (3.6) | 14 (5.1) | 1.51 (0.77–2.98) | |||||
| Dominant | A/A | 490 (70.2) | 184 (67.4) | 1.00 | 0.390 | 1,155.1 | 1,169.8 | |
| A/G-G/G | 208 (29.8) | 89 (32.6) | 1.14 (0.85–1.54) | |||||
| Recessive | A/A-A/G | 673 (96.4) | 259 (94.9) | 1.00 | 0.270 | 1,154.7 | 1,169.3 | |
| G/G | 25 (3.6) | 14 (5.1) | 1.47 (0.75–2.88) | |||||
| Overdominant | A/A-G/G | 515 (73.8) | 198 (72.5) | 1.00 | 0.690 | 1,155.7 | 1,170.4 | |
| A/G | 183 (26.2) | 75 (27.5) | 1.07 (0.78–1.46) | |||||
| Log-additive | --- | --- | --- | 1.15 (0.90–1.48) | 0.260 | 1,154.6 | 1,169.3 | |
| rs3803808 | Codominant | A/A | 246 (35.2) | 83 (30.4) | 1.00 | 0.180 | 1,154.4 | 1,173.9 |
| G/A | 340 (48.7) | 134 (49.1) | 1.18 (0.85–1.62) | |||||
| G/G | 112 (16.1) | 56 (20.5) | 1.47 (0.98–2.21) | |||||
| Dominant | A/A | 246 (35.2) | 83 (30.4) | 1.00 | 0.140 | 1,153.8 | 1,168.4 | |
| G/A-G/G | 452 (64.8) | 190 (69.6) | 1.25 (0.92–1.69) | |||||
| Recessive | A/A-G/A | 586 (83.9) | 217 (79.5) | 1.00 | 0.110 | 1,153.4 | 1,168 | |
| G/G | 112 (16.1) | 56 (20.5) | 1.34 (0.94–1.91) | |||||
| Overdominant | A/A-G/G | 358 (51.3) | 139 (50.9) | 1.00 | 0.870 | 1,155.9 | 1,170.5 | |
| G/A | 340 (48.7) | 134 (49.1) | 1.02 (0.77–1.36) | |||||
| Log-additive | --- | --- | --- | 1.21 (0.99–1.48) | 0.064 | 1,152.5 | 1,167.1 | |
| rs4078756 | Codominant | T/T | 384 (55.0) | 152 (55.7) | 1.00 | 0.930 | 1,157.8 | 1,177.3 |
| C/T | 277 (39.7) | 105 (38.5) | 0.97 (0.72–1.29) | |||||
| C/C | 37 (5.3) | 16 (5.9) | 1.08 (0.58–1.99) | |||||
| Dominant | T/T | 384 (55.0) | 152 (55.7) | 1.00 | 0.880 | 1,155.9 | 1,170.5 | |
| C/T-C/C | 314 (45.0) | 121 (44.3) | 0.98 (0.74–1.30) | |||||
| Recessive | T/T-C/T | 661 (94.7) | 257 (94.1) | 1.00 | 0.780 | 1,155.8 | 1,170.4 | |
| C/C | 37 (5.3) | 16 (5.9) | 1.09 (0.60–2.00) | |||||
| Overdominant | T/T-C/C | 421 (60.3) | 168 (61.5) | 1.00 | 0.780 | 1,155.8 | 1,170.4 | |
| C/T | 277 (39.7) | 105 (38.5) | 0.96 (0.72–1.28) | |||||
| Log-additive | --- | --- | --- | 1.00 (0.79–1.26) | 0.990 | 1,155.9 | 1,170.5 | |
| rs629367 | Codominant | A/A | 407 (58.3) | 176 (64.5) | 1.00 | 0.210 | 1,154.8 | 1,174.3 |
| C/A | 250 (35.8) | 82 (30.0) | 0.76 (0.56–1.03) | |||||
| C/C | 41 (5.9) | 15 (5.5) | 0.86 (0.46–1.60) | |||||
| Dominant | A/A | 407 (58.3) | 176 (64.5) | 1.00 | 0.084 | 1,152.9 | 1,167.5 | |
| C/A-C/C | 291 (41.7) | 97 (35.5) | 0.78 (0.58–1.04) | |||||
| Recessive | A/A-C/A | 657 (94.1) | 258 (94.5) | 1.00 | 0.870 | 1,155.9 | 1,170.5 | |
| C/C | 41 (5.9) | 15 (5.5) | 0.95 (0.52–1.75) | |||||
| Overdominant | A/A-C/C | 448 (64.2) | 191 (70.0) | 1.00 | 0.088 | 1,153.0 | 1,167.6 | |
| C/A | 250 (35.8) | 82 (30.0) | 0.77 (0.57–1.04) | |||||
| Log-additive | --- | --- | --- | 0.84 (0.66–1.06) | 0.140 | 1,153.7 | 1,168.3 | |
| rs7372209 | Codominant | C/C | 323 (46.3) | 117 (42.9) | 1.00 | 0.540 | 1,156.7 | 1,176.2 |
| T/C | 294 (42.1) | 126 (46.1) | 1.18 (0.88–1.59) | |||||
| T/T | 81 (11.6) | 30 (11.0) | 1.03 (0.65–1.66) | |||||
| Dominant | C/C | 323 (46.3) | 117 (42.9) | 1.00 | 0.340 | 1,155.0 | 1,169.6 | |
| T/C-T/T | 375 (53.7) | 156 (57.1) | 1.15 (0.86–1.52) | |||||
| Recessive | C/C-T/C | 617 (88.4) | 243 (89.0) | 1.00 | 0.830 | 1,155.8 | 1,170.5 | |
| T/T | 81 (11.6) | 30 (11.0) | 0.95 (0.61–1.49) | |||||
| Overdominant | C/C-T/T | 404 (57.9) | 147 (53.9) | 1.00 | 0.270 | 1,154.7 | 1,169.3 | |
| T/C | 294 (42.1) | 126 (46.1) | 1.17 (0.88–1.55) | |||||
| Log-additive | --- | --- | --- | 1.07 (0.87–1.31) | 0.540 | 1,155.5 | 1,170.2 |