TABLE 6.
The inheritance model analysis of these SNPs between CC and control groups.
| SNPs | Models | Genotypes | Control n (%) | CC n (%) | OR (95%CI) | p value | AIC | BIC |
|---|---|---|---|---|---|---|---|---|
| rs107822 | Codominant | T/T | 275 (39.4) | 139 (32.2) | 1.00 | 0.018 | 1,501.2 | 1,521.4 |
| C/T | 314 (45.0) | 202 (46.9) | 1.27 (0.97–1.67) | |||||
| C/C | 109 (15.6) | 90 (20.9) | 1.63 (1.15–2.31) | |||||
| Dominant | T/T | 275 (39.4) | 139 (32.2) | 1.00 | 0.015 | 1,501.4 | 1,516.5 | |
| C/T-C/C | 423 (60.6) | 292 (67.8) | 1.36 (1.06–1.76) | |||||
| Recessive | T/T-C/T | 589 (84.4) | 341 (79.1) | 1.00 | 0.026 | 1,502.3 | 1,517.4 | |
| C/C | 109 (15.6) | 90 (20.9) | 1.42 (1.05–1.94) | |||||
| Overdominant | T/T-C/C | 384 (55.0) | 229 (53.1) | 1.00 | 0.540 | 1,506.9 | 1,522.0 | |
| C/T | 314 (45.0) | 202 (46.9) | 1.08 (0.85–1.37) | |||||
| Log-additive | --- | --- | --- | 1.28 (1.08–1.51) | 4.6 x 10−3 | 1,499.0 | 1,514.0 | |
| rs10877887 | Codominant | T/T | 286 (41.0) | 185 (42.9) | 1.00 | 0.810 | 1,508.9 | 1,529.0 |
| T/C | 335 (48.0) | 200 (46.4) | 0.92 (0.72–1.19) | |||||
| C/C | 77 (11.0) | 46 (10.7) | 0.93 (0.61–1.40) | |||||
| Dominant | T/T | 286 (41.0) | 185 (42.9) | 1.00 | 0.520 | 1,506.9 | 1,522.0 | |
| T/C-C/C | 412 (59.0) | 246 (57.1) | 0.92 (0.72–1.18) | |||||
| Recessive | T/T-T/C | 621 (89.0) | 385 (89.3) | 1.00 | 0.860 | 1,507.2 | 1,522.3 | |
| C/C | 77 (11.0) | 46 (10.7) | 0.97 (0.66–1.42) | |||||
| Overdominant | T/T-C/C | 363 (52.0) | 231 (53.6) | 1.00 | 0.600 | 1,507.0 | 1,522.1 | |
| T/C | 335 (48.0) | 200 (46.4) | 0.94 (0.74–1.19) | |||||
| Log-additive | --- | --- | --- | 0.95 (0.79–1.14) | 0.570 | 1,507.0 | 1,522.0 | |
| rs2292832 | Codominant | T/T | 293 (42.0) | 209 (48.5) | 1.00 | 0.009 | 1,499.9 | 1,520.0 |
| T/C | 316 (45.3) | 189 (43.9) | 0.84 (0.65–1.08) | |||||
| C/C | 89 (12.8) | 33 (7.7) | 0.52 (0.34–0.80) | |||||
| Dominant | T/T | 293 (42.0) | 209 (48.5) | 1.00 | 0.033 | 1,502.7 | 1,517.8 | |
| T/C-C/C | 405 (58.0) | 222 (51.5) | 0.77 (0.60–0.98) | |||||
| Recessive | T/T-T/C | 609 (87.2) | 398 (92.3) | 1.00 | 0.006 | 1,499.8 | 1,514.9 | |
| C/C | 89 (12.8) | 33 (7.7) | 0.57 (0.37–0.86) | |||||
| Overdominant | T/T-C/C | 382 (54.7) | 242 (56.1) | 1.00 | 0.640 | 1,507.1 | 1,522.2 | |
| T/C | 316 (45.3) | 189 (43.9) | 0.94 (0.74–1.20) | |||||
| Log-additive | --- | --- | --- | 0.76 (0.64–0.92) | 0.004 | 1,499.0 | 1,514.0 | |
| rs353293 | Codominant | C/C | 499 (71.5) | 322 (74.7) | 1.00 | 0.460 | 1,507.7 | 1,527.8 |
| C/T | 180 (25.8) | 100 (23.2) | 0.86 (0.65–1.14) | |||||
| T/T | 19 (2.7) | 9 (2.1) | 0.73 (0.33–1.64) | |||||
| Dominant | C/C | 499 (71.5) | 322 (74.7) | 1.00 | 0.230 | 1,505.9 | 1,520.9 | |
| C/T-T/T | 199 (28.5) | 109 (25.3) | 0.85 (0.65–1.11) | |||||
| Recessive | C/C-C/T | 679 (97.3) | 422 (97.9) | 1.00 | 0.500 | 1,506.8 | 1,521.9 | |
| T/T | 19 (2.7) | 9 (2.1) | 0.76 (0.34–1.70) | |||||
| Overdominant | C/C-T/T | 518 (74.2) | 331 (76.8) | 1.00 | 0.320 | 1,506.3 | 1,521.4 | |
| C/T | 180 (25.8) | 100 (23.2) | 0.87 (0.66–1.15) | |||||
| Log-additive | --- | --- | --- | 0.86 (0.68–1.09) | 0.210 | 1,505.7 | 1,520.8 | |
| rs3746444 | Codominant | A/A | 490 (70.2) | 292 (67.8) | 1.00 | 0.560 | 1,508.1 | 1,528.3 |
| A/G | 183 (26.2) | 119 (27.6) | 1.09 (0.83–1.43) | |||||
| G/G | 25 (3.6) | 20 (4.6) | 1.34 (0.73–2.46) | |||||
| Dominant | A/A | 490 (70.2) | 292 (67.8) | 1.00 | 0.390 | 1,506.5 | 1,521.6 | |
| A/G-G/G | 208 (29.8) | 139 (32.2) | 1.12 (0.86–1.45) | |||||
| Recessive | A/A-A/G | 673 (96.4) | 411 (95.4) | 1.00 | 0.380 | 1,506.5 | 1,521.6 | |
| G/G | 25 (3.6) | 20 (4.6) | 1.31 (0.72–2.38) | |||||
| Overdominant | A/A-G/G | 515 (73.8) | 312 (72.4) | 1.00 | 0.610 | 1,507.0 | 1,522.1 | |
| A/G | 183 (26.2) | 119 (27.6) | 1.07 (0.82–1.41) | |||||
| Log-additive | --- | --- | --- | 1.12 (0.90–1.39) | 0.310 | 1,506.2 | 1,521.3 | |
| rs3803808 | Codominant | A/A | 246 (35.2) | 137 (31.8) | 1.00 | 0.400 | 1,507.4 | 1,527.5 |
| G/A | 340 (48.7) | 215 (49.9) | 1.14 (0.87–1.49) | |||||
| G/G | 112 (16.1) | 79 (18.3) | 1.27 (0.89–1.81) | |||||
| Dominant | A/A | 246 (35.2) | 137 (31.8) | 1.00 | 0.230 | 1,505.8 | 1,520.9 | |
| G/A-G/G | 452 (64.8) | 294 (68.2) | 1.17 (0.91–1.51) | |||||
| Recessive | A/A-G/A | 586 (83.9) | 352 (81.7) | 1.00 | 0.320 | 1,506.3 | 1,521.4 | |
| G/G | 112 (16.1) | 79 (18.3) | 1.17 (0.86–1.61) | |||||
| Overdominant | A/A-G/G | 358 (51.3) | 216 (50.1) | 1.00 | 0.690 | 1,507.1 | 1,522.2 | |
| G/A | 340 (48.7) | 215 (49.9) | 1.05 (0.83–1.33) | |||||
| Log-additive | --- | --- | --- | 1.13 (0.95–1.34) | 0.170 | 1,505.4 | 1,520.5 | |
| rs4078756 | Codominant | T/T | 384 (55.0) | 250 (58.0) | 1.00 | 0.450 | 1,507.7 | 1,527.8 |
| C/T | 277 (39.7) | 155 (36.0) | 0.86 (0.67–1.11) | |||||
| C/C | 37 (5.3) | 26 (6.0) | 1.08 (0.64–1.82) | |||||
| Dominant | T/T | 384 (55.0) | 250 (58.0) | 1.00 | 0.330 | 1,506.3 | 1,521.4 | |
| C/T-C/C | 314 (45.0) | 181 (42.0) | 0.89 (0.70–1.13) | |||||
| Recessive | T/T-C/T | 661 (94.7) | 405 (94.0) | 1.00 | 0.610 | 1,507.0 | 1,522.1 | |
| C/C | 37 (5.3) | 26 (6.0) | 1.14 (0.68–1.92) | |||||
| Overdominant | T/T-C/C | 421 (60.3) | 276 (64.0) | 1.00 | 0.210 | 1,505.7 | 1,520.8 | |
| C/T | 277 (39.7) | 155 (36.0) | 0.85 (0.67–1.10) | |||||
| Log-additive | --- | --- | --- | 0.94 (0.77–1.15) | 0.540 | 1,506.9 | 1,522.0 | |
| .rs629367 | Codominant | A/A | 407 (58.3) | 255 (59.2) | 1.00 | 0.580 | 1,508.2 | 1,528.3 |
| C/A | 250 (35.8) | 145 (33.6) | 0.93 (0.72–1.20) | |||||
| C/C | 41 (5.9) | 31 (7.2) | 1.21 (0.74–1.97) | |||||
| Dominant | A/A | 407 (58.3) | 255 (59.2) | 1.00 | 0.780 | 1,507.2 | 1,522.3 | |
| C/A-C/C | 291 (41.7) | 176 (40.8) | 0.97 (0.76–1.23) | |||||
| Recessive | A/A-C/A | 657 (94.1) | 400 (92.8) | 1.00 | 0.380 | 1,506.5 | 1,521.6 | |
| C/C | 41 (5.9) | 31 (7.2) | 1.24 (0.77–2.01) | |||||
| Overdominant | A/A-C/C | 448 (64.2) | 286 (66.4) | 1.00 | 0.460 | 1,506.7 | 1,521.8 | |
| C/A | 250 (35.8) | 145 (33.6) | 0.91 (0.71–1.17) | |||||
| Log-additive | --- | --- | --- | 1.01 (0.83–1.23) | 0.900 | 1,507.3 | 1,522.3 | |
| rs7372209 | Codominant | C/C | 323 (46.3) | 208 (48.3) | 1.00 | 0.130 | 1,505.2 | 1,525.3 |
| T/C | 294 (42.1) | 189 (43.9) | 1.00 (0.78–1.29) | |||||
| T/T | 81 (11.6) | 34 (7.9) | 0.65 (0.42–1.01) | |||||
| Dominant | C/C | 323 (46.3) | 208 (48.3) | 1.00 | 0.520 | 1,506.9 | 1,522.0 | |
| T/C-T/T | 375 (53.7) | 223 (51.7) | 0.92 (0.73–1.18) | |||||
| Recessive | C/C-T/C | 617 (88.4) | 397 (92.1) | 1.00 | 0.043 | 1,503.2 | 1,518.3 | |
| T/T | 81 (11.6) | 34 (7.9) | 0.65 (0.43–0.99) | |||||
| Overdominant | C/C-T/T | 404 (57.9) | 242 (56.1) | 1.00 | 0.570 | 1,506.9 | 1,522.0 | |
| T/C | 294 (42.1) | 189 (43.9) | 1.07 (0.84–1.37) | |||||
| Log-additive | --- | --- | --- | 0.88 (0.73–1.05) | 0.160 | 1,505.3 | 1,520.0 |