Table 2.
Comparison of Clinical Manifestations, Laboratory and Radiologic Findings in Hospitalized Elderly CAP Patients with or without CVEs (n=2941)
| Characteristics | With CVEs (n=402) | Without CVEs (n=2539) | p value |
|---|---|---|---|
| Clinical features | |||
| Fever | 213 (53.0) | 1328 (52.3) | 0.830 |
| Cough | 342 (85.1) | 2291 (90.2) | 0.003 |
| Chest pain | 23 (5.7) | 232 (9.1) | 0.022 |
| Wheezing | 256 (63.7) | 970 (38.2) | <0.001 |
| Cyanosis | 79 (19.7) | 297 (11.7) | <0.001 |
| Lower extremity edema | 132 (32.8) | 321 (12.6) | <0.001 |
| Mental confusion | 81 (20.1) | 151 (5.9) | <0.001 |
| RR≥24 beats/min | 42 (10.4) | 75 (3.0) | <0.001 |
| HR≥125 beats/min | 28 (7.0) | 45 (1.8) | <0.001 |
| Hypotension | 82 (20.4) | 384 (15.1) | 0.01 |
| Laboratory findings | |||
| WBC>10000/mm3 (n=2878) | 147 (37.3) | 769 (31.0) | 0.014 |
| HCT<30% (n=2811) | 85 (22.0) | 298 (12.3) | <0.001 |
| Cr>123.76 umol/L (n=2812) | 65 (17.0) | 213 (8.8) | <0.001 |
| Glucose>14 mmol/L (n=2698) | 20 (5.5) | 65 (2.8) | 0.009 |
| Na<130 mmol/L (n=2824) | 45 (13.6) | 146 (6.0) | <0.001 |
| BUN>7 mmol/L (n=2821) | 191 (50.0) | 674 (27.6) | <0.001 |
| PH<7.3 (n=1847) | 16 (5.2) | 28 (1.8) | 0.001 |
| PaO2<60 mmHg (n=1847) | 71 (23.3) | 250 (16.2) | 0.004 |
| SaO2<90% (n=1811) | 63 (21.6) | 156 (10.3) | <0.001 |
| Lactic acid>2 mmol/L (n=1175) | 44 (19.4) | 116 (12.2) | 0.007 |
| Albumin<25 g/L (n=2797) | 44 (11.7) | 161 (6.7) | 0.001 |
| Complications (n=2941) | |||
| Respiratory failure | 211 (52.5) | 299 (11.8) | <0.001 |
| Acute liver failure | 19 (4.7) | 24 (0.9) | <0.001 |
| Acute renal failure | 50 (12.4) | 24 (0.9) | <0.001 |
| DIC | 3 (0.7) | 1 (0) | 0.009 |
| Gastrointestinal bleeding | 45 (11.2) | 22 (0.9) | <0.001 |
| Radiology findings on CT | |||
| Multilobe infiltration (n=2941) | 225 (56.0) | 1121 (44.2) | <0.001 |
| Pleural effusion (n=2941) | 167 (41.5) | 566 (22.3) | <0.001 |
Abbreviations: CAP, community acquired pneumonia; CVE, cardiovascular event; RR, respiratory rate; HR, heart rate; WBC, white blood cell; HCT, hematocrit; Cr, creatinine; Na, sodium; BUN, blood urea nitrogen; PaO2, partial arterial oxygen pressure; SaO2, arterial oxygen saturation; DIC, disseminated intravascular coagulation; CT, computed tomography.