Table 2.
Total thiol, native thiol, disulfide, disulfide/native thiol, disulfide/total thiol, native thiol/total thiol and 8-OHdG/106dG ratios of the study and control groups
| Variable | OCD group (n = 35) | Healthy control group (n = 33) | 95 % CI | pvalue | |
|---|---|---|---|---|---|
|
| |||||
| Lower | Upper | ||||
| Total thiol (mmol/L) | 396.1 ± 58.8 | 464.6 ± 65.2 | −98.2 | −38.1 | 0.001 |
| Native thiol (mmol/L) | 358.9 ± 51.1 | 434.1 ± 60.4 | −72.1 | −16.1 | 0.003 |
| Disulfide (mmol/L) | 17.9 ± 6.87 | 14.1 ± 5.09 | 0.72 | 6.76 | 0.016 |
| Disulfide/native thiol (%) | 5.01 ± 1.84 | 3.28 ± 1.13 | 0.94 | 2.48 | 0.001 |
| Disulfide/total thiol (%) | 4.49 ± 1.52 | 3.06 ± 1.01 | 0.78 | 2.07 | 0.001 |
| Native thiol/total thiol (%) | 90.7 ± 3.44 | 93.8 ± 2.01 | −4.56 | −1.74 | 0.008 |
| 8-OHdG/106dG | 4.26 ± 1.11 | 2.74 ± 0.98 | 0.66 | 1.68 | 0.001 |
Values are presented as mean ± standard deviation.
OCD, obsessive compulsive disorder; CI, confidence interval.