Table 3.
Characteristics of subjects with subgroup analysis
| Variable | MPH start within 1 years after ADHD diagnosis (n = 625) | MPH start within 3 years after ADHD diagnosis (n = 789) |
|---|---|---|
| Sex, male | 502 (80.3) | 634 (80.4) |
| Exposure duration (yr) | 2.31 (0.84, 4.94) | 2.34 (0.82, 5.06) |
| Duration of MPH exposure before 1st MDD event (yr) | 1.00 (0.27, 2.57) | 0.91 (0.17, 2.46) |
| Duration of MPH exposure after MDD diagnosis (yr) | 0.51 (0.04, 2.18) | 0.60 (0.04, 2.29) |
| Age at MPH exposure (yr) | 8.00 (7.00, 9.00) | 8.00 (7.00, 9.00) |
| Age at ADHD diagnosis (yr) | 8.00 (7.00, 9.00) | 8.00 (7.00, 9.00) |
| Age at MDD diagnosis (yr) | 12.00 (9.00, 14.00) | 12.00 (9.00, 14.00) |
| No. of outpatient visit (n) | 155.00 (110.00, 222.00) | 168.00 (115.00, 229.00) |
| No. of psychiatric outpatient visit (n) | 59.00 (29.00, 95.00) | 62.00 (33.00, 101.00) |
| MPH prescription duration at each visit | 25.39 (16.80, 33.43) | 25.84 (16.89, 33.45) |
| Antidepressant use (d) | 107.00 (42.00, 280.00) | 112.00 (42.00, 317.00) |
Values are presented as number (%) or median (interquartile range).
MPH, methylphenidate; MDD, major depressive disorder; ADHD, Attention Deficit Hyperactivity Disorder.