TNF |
Tumor necrosis factor |
TACE |
TNF-converting enzyme |
TNFR2 |
TNF receptor type II |
TNFR1 |
TNF receptor type I |
mTNF |
Membrane TNF |
sTNF |
Soluble TNF |
mTNFR2 |
membrane TNFR2 |
sTNFR2 |
Soluble TNFR2 |
TNFRSF1B |
TNF receptor type II |
TILs |
Tumor-infiltrating lymphocytes |
THD |
TNF homology domain |
CRD |
cysteine-rich domain |
Tregs |
Regulatory T cells |
Teffs |
Effector T cells |
NK |
Natural killer |
IL |
Interleukin |
Th |
T Helper Type |
Foxp3 |
Forkhead Box P3 |
DD |
Death domain |
cIAP |
Cellular inhibitor of apoptosis pro ptosis protein |
FADD |
Fas-associated DD |
VEGFR2 |
vascular endothelial growth factor receptor 2 |
FLICE |
for FADD like ICE |
c-FLIP |
Cellular FLICE-like inhibitory protein |
TRAF |
TNFR-associated factor |
NF-κB |
Nuclear factor kappa B |
MDSCs |
Myeloid-derived suppressor cells |
MAPK |
Mitogen-activated protein kinases |
MSCs |
mesenchymal stem cells |
BAX |
BCL2-associated X protein |
JNK |
c-Jun N-terminal kinase |
PI3K |
Phosphoinositide 3-kinase |
IKKβ |
IκB Kinase beta |
Akt |
Protein Kinase B |
BMX/Etk |
bone marrow-expressed kinase |
NIK |
NF-κB-inducing kinase |
TISIDB |
Tumor and Immune System Interaction Database |
AIP1 |
apoptosis signal-regulating kinase 1 (ASK1)-interacting protein-1 |
BIRC3 |
cellular inhibitor of apoptosis 2 |
GEPIA |
Gene Expression Profiling Interactive Analysis |
NCR1 |
Natural cytotoxicity receptor 1 |
hnRNPK |
heterogeneous nuclear ribonuclear protein K |
YAP |
Yes-associated protein |
MLCK |
myosin light-chain kinase |
NKp46 |
natural killer cell p46 |
STAT |
signal transducer and activator of transcription |
mTOR |
Mammalian Target of Rapamycin |
c-FLIP |
Cellular FLICE-like inhibitory protein |
CTLA-4 |
Cytotoxic T Lymphocyte Antigen-4 |
TGF-β |
transforming growth factor-β |
PD1 |
programmed death-1 |
PDL1 |
programmed cell death receptor ligand 1 |
Ki67 |
Tumor proliferation marker |
LAG3 |
Lymphocyte-Activation Gene 3 |
Fc |
Fragment crystallisable |
VEGF |
vascular endothelial growth factor |
TCGA |
The Cancer Genome Atlas |
C-Jun |
transcription factor AP-1-like |
OS |
overall survival |
MLCK |
myosin light-chain kinase |
DFS |
disease-free survival |
CXCR4 |
C-X-C chemokine receptor 4 |
IFN-γ |
interferon-γ |
CXCL12 |
chemokine C-X-C motif ligand 12 |
p65 |
NF-kB subunit |
CSN5 |
constitutive photomorphogenic-9 signalosome |
ACC |
Adrenocortical Carcinoma |
BLCA |
Bladder Urothelial Carcinoma |
BRCA |
Breast invasive carcinoma |
COAD |
Colon adenocarcinoma |
DLBC |
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma |
CESC |
Cervical squamous cell carcinoma and endocervical adenocarcinoma |
CHOL |
Cholangiocarcinoma |
HNSC |
Head and Neck squamous cell carcinoma |
GBM |
Glioblastoma multiforme |
ESCA |
Oesophageal carcinoma |
KICH |
Kidney Chromophobe |
KIRC |
Kidney renal clear cell carcinoma |
KIRP |
Kidney renal papillary cell carcinoma |
LAML/AML |
Acute Myeloid Leukaemia |
LGG |
Brain Lower-Grade Glioma |
LIHC |
Liver hepatocellular carcinoma |
LUAD |
Lung adenocarcinoma |
LUSC |
Lung squamous cell carcinoma |
PAAD |
Pancreatic adenocarcinoma |
OV |
Ovarian serous cystadenocarcinoma |
PRAD |
Prostate adenocarcinoma |
PCPG |
Pheochromocytoma and Paraganglioma |
READ |
Rectum adenocarcinoma |
SARC |
Sarcoma |
SKCM |
Skin Cutaneous Melanoma |
STAD |
Stomach adenocarcinoma |
HLA-G |
human leucocyte antigen-G |
THCA |
Thyroid carcinoma |
THYM |
Thymoma |
UCEC |
Uterine Corpus Endometrial Carcinoma |
UCS |
Uterine Carcinosarcoma |
TNBC |
triple-negative breast cancer |
UVM |
Uveal Melanoma |
AICD |
Activation-induced Cell Death |
EPCs |
endothelial progenitor cell |