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. 2022 Apr 16;34:100430. doi: 10.1016/j.jbo.2022.100430

Fig. 3.

Fig. 3

High serum 2-HG levels are associated with poor prognosis. A. Scatter plots showing serum 2-HG levels in 20 patients, according to IDH mutation. B. Relationship between intratumoral and serum 2-HG levels in IDH-mutant chondrosarcoma. C. Relationship between tumor volume and serum 2-HG levels in IDH-mutant chondrosarcoma. D. Kaplan–Meier overall survival curves of IDH-mutant chondrosarcoma patients, according to serum 2-HG levels. Serum 2-HG levels were measured in samples acquired before the start of treatment. E. Kaplan–Meier disease-free survival curves of IDH-mutant chondrosarcoma patients without metastasis at first presentation, according to serum 2-HG levels.