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. 2022 Apr 13;34:100429. doi: 10.1016/j.jbo.2022.100429

Fig. 4.

Fig. 4

miR-384 regulates PTN expression and chemoresistance to chemotherapeutic agents, and these effects could be significantly reversed by PTN modulation. (A) miR-384 inhibitor could increase the expression of PTN and upregulate the chemoresistance to doxorubicin and cisplatin, while PTN downregulation could significantly reverse this effect. (B) miR-384 mimics could decrease the expression of PTN and downregulate the chemoresistance to chemotherapeutic agents, while PTN overexpression could significantly reverse this effect.