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. 2022 Mar 24;298(5):101865. doi: 10.1016/j.jbc.2022.101865

Figure 7.

Figure 7

The stoichiometry, assembly, and function of the NKA-regulatory complex.AE, alternative models of NKA-regulatory complex stoichiometry. The present data are consistent with Stoichiometry Model D. F, a model of conformational coupling in a dimer of α subunits. An energetically favorable catalytic step of one protomer (green arrow) assists a rate limiting step (red arrow) of the other partner, enhancing overall turnover. NKA, Na/K-ATPase.