Table 2.
Physiochemical properties of SARS-CoV-2 viral proteins.
| Gene symbol | Amino acids | Molecular weight | Theoretical pIa | Extinction coefficient (M-1 cm-1) | Half-life in mammalian cells (hours) | Instability index | Aliphatic index | GRAVYb |
| orf10 | 38 | 4449.23 | 7.93 | 4470 | 30 | 16.06 (stable) | 107.63 | 0.637 |
| orf8 | 121 | 13,804.93 | 5.42 | 16,305 | 30 | 46.24 (unstable) | 94.13 | 0.181 |
| orf7a | 121 | 13,744.17 | 8.23 | 7825 | 30 | 48.66 (unstable) | 100.74 | 0.318 |
| orf6 | 61 | 7272.54 | 4.60 | 8480 | 30 | 31.16 (stable) | 130.98 | 0.233 |
| orf3a | 275 | 31,122.94 | 5.55 | 58,705 | 30 | 32.96 (stable) | 103.42 | 0.275 |
| M | 222 | 25,146.62 | 9.51 | 52,160 | 30 | 39.14 (stable) | 120.86 | 0.446 |
| E | 75 | 8365.04 | 8.57 | 6085 | 30 | 38.68 (stable) | 144.00 | 1.128 |
| S | 1273 | 141,206.52 | 6.24 | 148,960 | 30 | 33.01 (stable) | 84.82 | –0.077 |
| S | 1272 | 140,972.27 | 6.16 | 147,470 | 30 | 32.78 (stable) | 85.05 | –0.071 |
| N | 88 | 9827.08 | 10.23 | 8480 | 4.4 | 36.54 (stable) | 61.14 | –1.067 |
| N | 133 | 14,363.88 | 11.37 | 8480 | 1 | 58.97 (unstable) | 44.21 | –1.170 |
| N | 419 | 45,625.70 | 10.07 | 43,890 | 30 | 55.09 (unstable) | 52.53 | –0.971 |
apI: isoelectric point.
bGRAVY: grand average of hydropathicity.