FIG. 5.

Log-10 cumulative p24 (pg/mL-mg) from four rectal tissue biopsies versus DPV concentration in rectal tissue biopsies collected at the same time, with a linear fit from a mixed effects model (samples with DPV concentration BLQ from participants in the DPV gel arm were imputed a value of LLOQ/2 while samples from participants in the Placebo gel arm were imputed a value of LLOQ/20). The light gray and dark gray regions indicate the range and interquartilc range, respectively, of the LLOQs for the cumulative p24 (horizontal gray bars) and the DPV concentration (vertical gray bars). BLQ, below the lower limit of quantification. Color images are available online.