Table 1.
N = 481 | |
Age (years) | |
Mean (SD) | 44.0 (12.7) |
Median (IQR) | 42.0 (35.0–52.0) |
Sex, n (%) | |
Female | 432 (89.8) |
Male | 49 (10.2) |
Indication for levothyroxine, n (%) | |
Chronic (autoimmune) thyroiditis | 422 (88.4) |
Postsurgical | 25 (5.2) |
Total thyroidectomy and radioiodine ablation for thyroid carcinoma | 16 (3.3) |
Radioiodine ablation | 8 (1.6) |
Postpartum thyroiditis | 6 (1.2) |
Pregnancy, n (%) | |
Pregnant women | 62 (14.4) |
Diabetes, n (%) | |
Normal glucose tolerance | 271 (56.3) |
Prediabetes | 149 (31.0) |
T2DM | 47 (9.8) |
BMI (kg/m2) | |
Mean (SD) | 30.0 (6.0) |
Median (IQR) | 29.4 (25.7–33.3) |
Lipid profile | |
TC (mmol/L) | |
Mean (SD) | 4.7 (0.9) |
Median (IQR) | 4.7 (4.1–5.3) |
LDL (mmol/L) | |
Mean (SD) | 3.1 (0.8) |
Median (IQR) | 3.0 (2.5–3.6) |
HDL (mmol/L) | |
Mean (SD) | 1.4 (0.4) |
Median (IQR) | 1.4 (1.2–1.7) |
Triglycerides (mmol/L) | |
Mean (SD) | 1.2 (0.6) |
Median (IQR) | 1.1 (0.8–1.5) |
Thyroid function | |
TSH (μIU/mL) | |
Mean (SD) | 3.7 (9.2) |
Median (IQR) | 2.0 (0.8–3.7) |
fT4 (pmol/L) | |
Mean (SD) | 17.1 (4.1) |
Median (IQR) | 16.9 (14.6–19.3) |
fT3 (pmol/L) | |
Mean (SD) | 4.3 (0.8) |
Median (IQR) | 4.2 (3.9–4.6) |
Levothyroxine dose (mg) | |
Mean (SD) | 85.57 (42.4) |
Median (IQR) | 78.57 (50–100) |
Interfering medications, n (%) | |
Iron supplements | 55 (11.4%) |
Calcium supplements | 45 (9.4%) |
Proton pump inhibitors | 34 (7.1%) |
Data are shown as n (%) or mean (SD) and median (IQR).
BMI, body mass index; fT3, free triiodothyronine; fT4, free thyroxine; HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein; SD, standard deviations; T2DM, type 2 diabetes; TC, total cholesterol; TSH, thyrotropin.