TABLE 2.
BT bacteriostatic and bactericidal concentrations against S. aureusa
| BT | MIC (μM Bi3+) | MBC (μM Bi3+) |
|---|---|---|
| BisTOL | 4.4 ± 0.1 | 8.8 ± 0.3 |
| BisPYR | 6.7 ± 0.2 | 14.2 ± 0.8 |
| BisBAL | 8.3 ± 0.4 | 18.0 ± 0.5 |
| BisEDT | 2.4 ± 0.0 | 73.3 ± 2.3 |
a
As determined for S. aureus ATCC 25923 by broth dilution. The broth consisted of Mueller-Hinton broth with 1% Fildes enrichment and 20 mM NaCl. BTs, prepared in propylene glycol at a 2:1 molar ratio, were added to medium containing bacteria in accordance with NCCLS standards. The data represent the means resulting from three or more independent trials. Five micromolar BT contains approximately 1 μg of bismuth/ml.