TABLE 3.
Agent | Bacteria | MIC (μM) |
---|---|---|
BisBAL 3:1 | 87 S. aureus isolates | 5.5 ± 0.9 |
BisPYR 2:1 | 1 MRSA clinical strain | 2.5 |
BisEDT 2:1 | 10 MRSE clinical strains | 1.1 ± 0.4 |
BisEDT 2:1 | S. aureus ATCC 25923 | 2.4 |
BisEDT 2:1 | S. epidermidis ATCC 12228 | 0.09 |
BisßME 1:1.4 | 65 S. aureus clinical strains | 23.7 ± 4.7 |
Dilutions (1:100) of a 0.5 MacFarland standard suspension of staphylococci in Mueller-Hinton broth containing 1% Fildes enrichment and 20 mM NaCl were incubated at 34°C with rocking in an Abbott Avantage. Five micromolar bismuth-thiol contains approximately 1 μg of bismuth/ml.