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. Author manuscript; available in PMC: 2022 Apr 28.
Published in final edited form as: Autism Res. 2021 Dec 29;15(3):539–550. doi: 10.1002/aur.2663

TABLE 4.

Variables that most contributed to the heterogeneity and homogeneity among preschool-aged children with autism spectrum disorder and those with subthreshold characteristics in the Study to Explore Early Development Phase1 and Phase2

Autism spectrum disorder Subthreshold characteristics
SEED1 SEED2 SEED1 SEED2
Heterogeneity Dimension 1: Dysregulation Anxiety/depression + + + +
Sleep problems + + + +
Aggression + + + +
No sensory dysfunction + +
Emotional reactivity + +
Heterogeneity Dimension 2: Developmental abilities Expressive language skills + + + +
Receptive language skills + + + +
Fine motor skills + +
Visual reception skills + +
Visual reception delays + +
Homogeneity Sensory dysfunction + +
Age of walking 15 months or younger + +
Absence of epilepsy/seizure disorder + + + +
Absence of developmental regression + +
Absence of moderate–severe ASD symptoms + +

Note: Developmental skills in Dimension 2 in the average range unless otherwise noted.