TABLE 4.
Variables that most contributed to the heterogeneity and homogeneity among preschool-aged children with autism spectrum disorder and those with subthreshold characteristics in the Study to Explore Early Development Phase1 and Phase2
Autism spectrum disorder | Subthreshold characteristics | ||||
---|---|---|---|---|---|
SEED1 | SEED2 | SEED1 | SEED2 | ||
Heterogeneity Dimension 1: Dysregulation | Anxiety/depression | + | + | + | + |
Sleep problems | + | + | + | + | |
Aggression | + | + | + | + | |
No sensory dysfunction | + | + | |||
Emotional reactivity | + | + | |||
Heterogeneity Dimension 2: Developmental abilities | Expressive language skills | + | + | + | + |
Receptive language skills | + | + | + | + | |
Fine motor skills | + | + | |||
Visual reception skills | + | + | |||
Visual reception delays | + | + | |||
Homogeneity | Sensory dysfunction | + | + | ||
Age of walking 15 months or younger | + | + | |||
Absence of epilepsy/seizure disorder | + | + | + | + | |
Absence of developmental regression | + | + | |||
Absence of moderate–severe ASD symptoms | + | + |
Note: Developmental skills in Dimension 2 in the average range unless otherwise noted.