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. 2022 Apr 14;13:881038. doi: 10.3389/fmicb.2022.881038

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Copyright © 2022 Choi, Jeon, Won, Kang, Lee and Kee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation of surrogate virus neutralization test (sVNT) with the binding antibody assays in 389 samples from 199 COVID-19 patients. (A) Abbott vs. sVNT. (B) Roche vs. Siemens. (C) Siemens vs. sVNT. (D) SDF IgM vs. sVNT. (E) SDF IgG vs. sVNT. Each triangle represents an individual positive sample. Correlation between two measures was performed using Spearman ρ (95% confidence interval). The horizontal and vertical dotted lines indicate the cut-off value of each assay. Abbott, SARS-CoV-2 IgG (Abbott); COI, cut-off index; %I, percentage inhibition; Roche, Elecsys Anti-SARS-CoV-2 (Roche); S/C, sample/calibrator; S/CO, sample/cut-off; SDF, STANDARD F COVID-19 IgM/IgG Combo FIA (SD BIOSENSOR); Siemens, ADVIA Centaur SARS-CoV-2 Total (Siemens); sVNT, surrogate virus neutralization test.