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| Human gene | Protein | Substrates | Tissue distribution |
|---|---|---|---|
| SLC5A1 | SGLT1 | Glucose and galactose | Small intestine, kidney and heart |
| SLC5A2 | SGLT2 | Glucose | Kidney |
| SLC5A4 | SGLT3 | Na+ (H+) | Small intestine, skeletal muscle, kidney, uterus and testis |
| SLC5A8 | SGLT4 | — | Small intestine, kidney, liver, lung and brain |
| SLC5A9 | SGLT5 | — | Kidney |
| SLC5A10 | SGLT6 | Chiro-inositol, myo-inositol, glucose and xylose | Small intestine, kidney, liver, heart, lung and brain |
