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. 2022 Apr 14;28(14):1444–1454. doi: 10.3748/wjg.v28.i14.1444

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Transplanted three-dimensional liver tissue culture models in partially hepatectomized model mice. A: A schematic illustration showing the transplantation of the three-dimensional (3-D) liver tissue culture model; B: Histological analyses and hematoxylin-eosin staining of the section for the 3-D liver tissue culture model after transplantation; C: Higher magnification of the inscribed area in (B). The vascularization was observable at condensed collagen fibril matrices. Arrowheads indicate new blood vessels; D: Immunohistochemical analysis of the 3-D liver tissue culture model of albumin-positive hepatic cells after being transplanted using anti-albumin (green) antibodies. Bar corresponds to 100 μm.