Fig. 11. Photograph (magnification = 40×, scale = 50 μm) shows immunohistochemical expression of caspase-3 in MCAO model in control (N), ischemic (I) and treatment groups of nanocomposite doses ND1 (1 μg per kg b. wt), ND2 (10 μg per kg b. wt), ND3 (100 μg per kg b. wt) and free curcumin (FD) (100 μg per kg b. wt). Control (N) group shows almost no expression for caspase-3 marker whereas the ischemic (I) group shows maximum expression. Treatments ND1 and ND2 show moderate to mild expression but less than, ND3 shows minimum expression.