FIG. 5.

Exacerbation of myocarditis by virus reinfection is prevented with antiviral therapy. BALB/c mice were inoculated with 10⁴ PFU of MCMV (K181 strain) i.p. on day 0. The mice were then reinfected with 10⁴ PFU of either K181 (K181/K181) or G4 (K181/G4) MCMV i.p. on day 56 p.i. and then treated with either GCV at 40 mg/kg/day or CDV at 5 mg/kg/day from day 57 to day 63 p.i. or treated with saline as a placebo. The average numbers (+ SD) of inflammatory foci per heart section at day 63 p.i. from groups of five mice are shown.