Skip to main content
. Author manuscript; available in PMC: 2022 Apr 28.
Published in final edited form as: Oncogene. 2007 Oct 29;27(18):2552–2560. doi: 10.1038/sj.onc.1210896

Figure 4.

Figure 4.

Overexpression of CCN3 in melanoma cells decreases MMP-2/−9 activities. (a and b) Downregulated MMP-2 (a) and MMP-9 (b) mRNA expression in 1205Lu cells transduced with CCN3 lentiviral vector as compared to LacZ-transduced cells. Results are presented as relative levels to those of GAPDH by quantitative RT-PCR. The data are expressed as means±s.d. with n=4 (*P<0.05, Student’s t-test). (c) Serum-free conditioned media from 1205Lu cells transduced with control LacZ or CCN3 were analysed by collagen zymography. Shown is a representative zymogram of three independent experiments.