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. 2022 Apr 28;12:6978. doi: 10.1038/s41598-022-10928-z

Table 2.

Associations with cardiac arrest and acute coronary syndrome calls among those aged 16–39 using a negative binomial regression model, with and without stepwise BIC feature selection.

Variable With stepwise BIC selection Without feature selection
Adjusted incidence rate ratio (95% CI) P-value Adjusted incidence rate ratio (95% CI) P-value
The bi-weekly cumulative counts of 1st and 2nd vaccine doses in the age group 16–39, normalized by the respective population size 3.32 (2.12–5.14)  < 0.001 2.20 (1.06–4.56)  < 0.05
The three-week cumulative new COVID-19 infection count among the age group 16–39, normalized by the respective population size 26.94 (0.03–20,067.17) 0.330
Call type: Acute coronary syndrome 1 [Reference] 1 [Reference]
Call type: Cardiac arrest 0.24 (0.22–0.25)  < 0.001 0.24 (0.22–0.25)  < 0.001
Week not during a COVID-19 public health advisory 1 [Reference] 1 [Reference]
Week during a COVID-19 public health advisory 0.94 (0.85–1.04) 0.224
Year: 2019 0.88 (0.83–0.94)  < 0.001 0.83 (0.75–0.92)  < 0.001
Year: 2020 0.94 (0.84–1.05) 0.245
Year: 2021 1 [Reference] 1 [Reference]

BIC Bayesian information criterion, CI confidence interval, COVID-19 coronavirus disease 2019.