Fig. 4. (a) Pathway analysis of metabolic changes in serum samples after geniposide treatment. (1) Phenylalanine, tyrosine and tryptophan biosynthesis; (2) phenylalanine metabolism; (3) arachidonic acid metabolism; (4) glyoxylate and dicarboxylate metabolism; (5) arginine and proline metabolism; (6) pyruvate metabolism; (7) citrate cycle (TCA cycle); (8) alanine, aspartate and glutamate metabolism; (9) glycolysis or gluconeogenesis; (10) sphingolipid metabolism; (11) glycerophospholipid metabolism; (12) starch and sucrose metabolism; (13) steroid hormone biosynthesis; (14) galactose metabolism; (15) primary bile acid biosynthesis; (16) cysteine and methionine metabolism. (b) The metabolic pathway influences the value of different pathways.