Formulation composition and physicochemical characterization of PLGA NPs of rivaroxaban (n = 3).
Formulation composition | Characterization parameter | ||
---|---|---|---|
Rivaroxaban (mg) | 20 | Particle size ± SD (nm) | 496.00 ± 8.50 |
PLGA (mg) | 125 | Polydispersity index | 0.47 |
PVA (mg) | 500 | Zeta potential ± SD (mV) | −18.41 ± 3.14 |
Entrapment efficiency ± SD (%) | 87.91 ± 8.60 |