Inhibitory activities of indicated compounds against ACL and NF-κB.

Compound	IC50a (μM)
	ACL	NF-κB
7	12.5 ± 5.1	>50
11	2.8 ± 0.9	16.8 ± 1.1
12	10.6 ± 0.1	>50
BMS 303141b	0.4 ± 0.1	NTd
PS-341c	NTd	0.06 ± 0.01

^aThese data are expressed as the mean ± SEM of triplicated experiments.

^bPositive control for the ACL assay.

^cPositive control for the NF-κB assay.

^dNT: not tested.