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. 2022 Apr 4;13:825828. doi: 10.3389/fmicb.2022.825828

TABLE 3.

Anti-biofilm depolymerase studies.

Author, year Biofilm-forming bacteria Phage(s) Growth site Results
Shahed-Al-Mahmud et al., 2021 A. baumannii φAB6 96-well microtiter plate Showed a therapeutic effect in the treatment of A. baumannii-induced infections
Chen et al., 2021 A. baumannii vB_AbaM-IME-AB2 96-well plate Total eradication of human serum bacteria at 50% volume ratio when combination of phage and colistin was applied.
Ku et al., 2021 P. mirabilis KMI8 96 well polystyrene plates Capable of degrading mono-biofilms of a strain of Klebsiella michiganensis (K. michiganensis) that carried the polysaccharide capsule KL70 locus
Rice et al., 2021 K. michiganensis vB_PmiS_PM-CJR LB agar plates Characterized a biofilm depolymerase from a Proteus phage
Wu et al., 2019 K. pneumoniae SH-KP152226 96-well plate Specific enzymatic activities in the depolymerization of the K47 capsule Enhance polymyxin activity against K. pneumoniae biofilms
Guo et al., 2017 E. coli vB_EcoM_ECOO78 96-well microtiter plate New potential strategy for preventing E. coli biofilm formation