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. 2022 Apr 24;15:1281–1291. doi: 10.2147/DMSO.S362424

Table 2.

Studies on Prevalence of NAFLD in PCOS

Size Diagnostic Criteria for PCOS Diagnostic Basis for NAFLD Prevalence (%) Region Author, Year, and Reference
PCOS Control PCOS Control
200 - NIH ALT 14.50 - U.S.A Setji, 200618
88 - NIH Ultrasonography 54.50 - U.S.A Gambarin-Gelwan, 200619
41 31 Rotterdam Ultrasonography 41.50 19.40 Chile Cerda, 200720
ALT 39.00 3.20
57 60 AES Ultrasonography 36.80 20.00 Greece Vassilatou, 201021
ALT 22.80 3.30
192 73 AES LIFL 34.00 6.90 Germany Tan, 201022
CK18-M30 27.60 1.40
34 32 Rotterdam Liver biopsy 44.00 20.80 U.S.A Hossain, 201123
45 32 Rotterdam Ultrasonography 73.30 46.70 Brazil Zueff, 201224
54 55 Rotterdam Ultrasonography 66.70 25.40 India Karoli, 201325
ALT 31.40 7.30
602 588 Rotterdam Ultrasonography 32.90 18.50 China Qu, 201326
184 125 Rotterdam Ultrasonography 57.60 49.60 Poland Bohdanowicz-Pawlak, 201427
103 34 AES Ultrasonography 23.80 3.30 Brazil Romanowski, 201528
600 125 Rotterdam LFS 50.60 34.00 Greece Macut, 201629
400 100 Rotterdam Ultrasonography 56.25 30.80 China Cai, 201730
75 75 Rotterdam Ultrasonography 38.70 18.70 Iran Mehrabian, 201731
202 101 Rotterdam HSI 68.80 33.30 Italy Petta, 201732
188 65 Rotterdam Ultrasonography 44.68 24.62 China Zhang, 201833
60 - Rotterdam Ultrasonography 38.30 - India Harsha Varma, 201934
98 98 Rotterdam CAP 69.30 34.60 Mexico Salva-Pastor, 202035
70 60 Rotterdam Ultrasonography 38.57 6.67 India Chakraborty, 202036
87 40 Rotterdam Ultrasonography 77.00 52.50 Brasil Taranto, 202037
101 - Rotterdam CAP 39.60 - Canada Shengir, 202038

Abbreviations: PCOS, polycystic ovary syndrome; NAFLD, nonalcoholic fatty liver disease; NIH, National Institutes of Health; AES, androgen excess society; U.S.A, United States of America; ALT, alanine aminotransferase; LIFL, liver injury implicating fatty liver; CK18-M30, cytokeratin 18-M30; LFS, liver fat score; HSI, hepatic steatosis index; CAP, controlled attenuation parameter.