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Fluorescence imaging of Dylight680-labeled Fv-LDP-D3 in KYSE520 and KYSE150 xenograft-bearing nude mice. (A) Electrophoresis of DyLight680-labeled Fv-LDP-D3. (B) In vivo fluorescence imaging of KYSE520 and KYSE150 xenograft athymic mouse models after injection of 20 mg/kg Fv-LDP-D3 via the tail vein. (C) In vitro fluorescence images; 1–7 representing tumor, heart, liver, spleen, kidney, small intestine, and femur taken from the dissected xenograft-bearing mice, respectively.
